The Wyss Zurich Translational Center (Wyss Zurich) is a joint accelerator of the ETH Zurich and the University of Zurich, which was made possible by a generous donation from the Swiss entrepreneur and philanthropist Dr. hc. mult. Hansjörg Wyss. The mission of Wyss Zurich is to drive the clinical translation and technology transfer of outstanding scientific discoveries into new therapies for patients and breakthrough innovations in the emerging fields of Regenerative Medicine and Robotics and to promote hybrid technologies in these fields. Wyss Zurich brings together some of the world’s leading experts to form multidisciplinary teams, pooling their knowledge and expertise.

The project Recolony is focused on the development of a bacteria-based therapy for colorectal cancer that primarily consists of selected bacteria of the gut microbiota. These bacteria have an enormous influence on the immune system and are able to provoke and enhance an immune reaction against cancer. The bacteria will be orally applied in gastro-resistant capsules with a colonic release. With this approach, Recolony aims to develop a new class of drugs for the treatment and prevention of cancer.

• Plan and design experiments and research protocols.
• Perform experiments with different mouse tumour models to explore efficacy, safety, toxicology, mode of action, treatment dosage requirements and other research questions.
• Work with anaerobic bacteria chamber, handling different anaerobic bacteria.
• Work in cell culture with different cell lines as well as primary human and mouse cells.
• Process and run samples using flow cytometry, perform histology stainings, gene expression analysis etc.
• Manage lab inventory and order of supplies.
• Analyze, document and report research results according to GLP-like standards.

• Master’s degree or PhD in life science, with several years of research experience
• Experience with in vivo experimentation in mice (LTK 1 or equivalent) preferred
• A solid background in cell culture and microbiology techniques
• Knowledge of GLP standards is an advantage
• Ability to work independently in an organized manner
• A dynamic team player, who is taking initiative and has good communication skills
• High proficiency in English in written and spoken form

This is a unique opportunity to join a young, dynamic and growing start-up team developing tomorrow’s treatment against cancer. You will benefit from an inspiring and socially relevant environment.

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish.

We look forward to receiving your online application with the following documents:

• CV
• Cover Letter
• Recommendation Letter

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.
Further information about Wyss Zurich Translational center can be found on our website 
Further information about Recolony can be found on our website 

Questions regarding the position should be directed to  Dr Ana Montalban-Arques, ana.montalban@wysszurich.ch (no applications).

For recruitment services the GTC of ETH Zurich apply.

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.